Basic Information
VIS ID
TVIS30005585
Fusion event
HIV-CREM integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p11.21
Reference genome
GRCh37/hg19
Start
35443633/35154705 (Hg38)
End
35443633/35154705 (Hg38)
Orient
-
Location type
Intronic
Target gene
CREM
miRNAs that regulate target gene
hsa-let-7c-5p ; hsa-mir-3117-3p ; hsa-mir-30e-5p ; hsa-mir-30d-5p ; hsa-mir-30c-5p ; hsa-mir-30b-5p ; hsa-mir-30a-5p ; hsa-mir-1288-3p ; hsa-mir-4312 ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-8083 ; hsa-mir-3169 ; hsa-mir-4759 ; hsa-mir-562
Nearest miRNA
hsa-mir-1265/Upstream/75025; hsa-mir-107/Downstream/486467;
Nearest TSS
ENST00000439456/Upstream/6304; ENST00000497686/Downstream/12811;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/26948, chr10-CpG: 23/Downstream/60175
Nearest cancer related gene
CREM(TSG, No orient, 0)
Upstream sequence
CCCTGGCTGTTTTTCATGGTTCATATTTTATCTGTTACACAGAACATTTGTATTCTGTTAGAATTATCTATAAAAATGAACAAAGGATGGAAGAAAAAGG
Downstream sequence
AAGAGAGTAATTTTTTTCAATAAATGCTAAATCTGTATTATAAAATGTTCCTTAGTCATCCAATTCAGAAAAACCCACTGCTTTGAACCGTAACTCATTA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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