Basic Information
VIS ID
TVIS30005615
Fusion event
HIV-HK1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
71085307/69325551 (Hg38)
End
71085307/69325551 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10C
Target gene
HK1
miRNAs that regulate target gene
hsa-mir-30a-5p ; hsa-mir-1296-5p ; hsa-mir-615-3p ; hsa-mir-99b-5p ; hsa-mir-23b-3p ; hsa-mir-10b-5p ; hsa-mir-10a-5p ; hsa-mir-93-5p ; hsa-let-7b-5p
Nearest miRNA
hsa-mir-1265/Upstream/1922141; hsa-mir-107/Downstream/2465196;
Nearest TSS
ENST00000439456/Upstream/6698; ENST00000494253/Downstream/12469;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/5930, chr10-CpG: 47/Downstream/83098
Upstream sequence
ggttcaagcgattctcctgcctcagcctcctgagtagctgggattacaggcaccagccaatgctcctggcCTGCAtttttttttttttttttgagatggg
Downstream sequence
gtctcactctgtatcctgggttggagtgcagtggtgtgatctcagctcactgaaacctccatctcgcgggttcaagtgatacttctgcctcagtgccccc
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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