Basic Information
VIS ID
TVIS30005664
Fusion event
HIV-TLL2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
98143592/96383835 (Hg38)
End
98143592/96383835 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10D
Target gene
TLL2
miRNAs that regulate target gene
hsa-mir-944 ; hsa-mir-4803 ; hsa-mir-548c-3p ; hsa-mir-514b-3p ; hsa-mir-514a-3p ; hsa-mir-2277-3p
Nearest miRNA
hsa-mir-107/Upstream/319436; hsa-mir-1287/Downstream/444834;
Nearest TSS
ENST00000439456/Upstream/8474; ENST00000469510/Downstream/130076;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/253180, chr10-CpG: 20/Downstream/707
Upstream sequence
tcagcctcacgagtagctgggattacaggcacacaccaccacgcccggctaatttttttttttttttttgtatttttagtagagacggcgtttcaccatg
Downstream sequence
ttggccaggctggtctagaactcctgacctagtgatctgcccgcctcggcctcccaaagtgctgggattacaggcatgagccaccacgcccggcctaaac
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate