Basic Information
VIS ID
TVIS30005669
Fusion event
HIV-ERLIN1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q24.31
Reference genome
GRCh37/hg19
Start
101935969/100176212 (Hg38)
End
101935969/100176212 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Target gene
ERLIN1
miRNAs that regulate target gene
hsa-mir-34a-5p ; hsa-mir-30a-5p ; hsa-mir-615-3p ; hsa-mir-10b-5p ; hsa-mir-10a-5p ; hsa-mir-30c-5p ; hsa-mir-17-5p ; hsa-mir-218-5p ; hsa-mir-30e-5p ; hsa-mir-30d-5p ; hsa-mir-30b-5p
Nearest miRNA
hsa-mir-107/Upstream/1251644; hsa-mir-1307/Downstream/798773;
Nearest TSS
ENST00000439456/Upstream/94335; ENST00000443919/Downstream/9817;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/60830, chr10-CpG: 43/Downstream/9602
Upstream sequence
ACACAGGTACCTTCAAATTCAGCCAGGGTAAAAGTCAGGGTGATATATTACACATGAGGAAAAGTGCCAACAAAATAGTGAAACCAAAAACCACAACTAA
Downstream sequence
CAAATCTTGATGTGTTGCTTGTGCTCAATTTTCCAAATACCCTTGCATTTGTAATACTAATGCCAAACACCTGCTGGTTAGCCCATCAAACAGGGGCTAA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate