Basic Information
VIS ID
TVIS30005684
Fusion event
HIV-CUEDC2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q24.32
Reference genome
GRCh37/hg19
Start
104191085/102431328 (Hg38)
End
104191085/102431328 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Target gene
CUEDC2
miRNAs that regulate target gene
hsa-mir-615-3p ; hsa-mir-324-5p ; hsa-mir-331-3p ; hsa-mir-186-5p
Nearest miRNA
hsa-mir-107/Upstream/829831; hsa-mir-1307/Downstream/5184;
Nearest TSS
ENST00000439456/Upstream/7024; ENST00000428200/Downstream/1240;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/9043, chr10-CpG: 45/Downstream/899
Upstream sequence
tccctggttcaagcaattcccctgcctcagcctcctgagtagctgggattacagtcgcatgccaccatgcctggcaaatttattttgtattttttagtag
Downstream sequence
agacggggtttcaccatgttggccagactggtctcgaactcctgacctcaggcaatccacccgcctcggtctcccaaagtgctgggattacaggcatgaa
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate