Basic Information
VIS ID
TVIS30005697
Fusion event
HIV-chr10 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q25.2
Reference genome
GRCh37/hg19
Start
114672759/112913000 (Hg38)
End
114672759/112913000 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Target gene
LOC107984158 ; VTI1A
miRNAs that regulate target gene
hsa-mir-18a-3p ; hsa-mir-18b-5p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-6891-3p ; hsa-mir-452-3p ; hsa-mir-5581-5p ; hsa-mir-4297 ; hsa-mir-302a-5p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-205-5p ; hsa-mir-6793-3p ; hsa-mir-532-5p ; hsa-mir-141-5p ; hsa-mir-519d-3p ; hsa-mir-93-5p ; hsa-mir-20b-5p ; hsa-mir-17-5p
Nearest miRNA
hsa-mir-107/Upstream/278746; hsa-mir-202/Downstream/864993;
Nearest TSS
ENST00000439456/Upstream/235181; ENST00000346198/Downstream/37250;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/465438, chr10-CpG: 34/Downstream/36890
Nearby gene
TCF7L2(No orient, 37250)
Upstream sequence
TTCTGAATAAACGCAGAAGCAATCAAATGCTCTAGAGTTGTTGGGCTTAAATATCAGTCATGCTTCATCGCAGGCATGCAGGACCTGTTCCTTGTATGAT
Downstream sequence
ATCGTCATATAAAGATTAAGGACCTTAGGGGCATCTTAATGAGGTGATAATGAGGAAAAAATGTTCTGGTTTTGGGGGGGAGCTGTAGTCTTTACTTTCA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate