Basic Information
VIS ID
TVIS30005698
Fusion event
HIV-TRUB1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
116716392/114956633 (Hg38)
End
116716392/114956633 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Target gene
TRUB1
miRNAs that regulate target gene
hsa-mir-17-5p ; hsa-mir-153-3p ; hsa-mir-455-5p ; hsa-mir-4729 ; hsa-mir-5700 ; hsa-mir-194-5p ; hsa-mir-4426 ; hsa-mir-4451 ; hsa-mir-4647 ; hsa-mir-4662b ; hsa-mir-4775 ; hsa-mir-510-3p ; hsa-mir-548g-3p ; hsa-mir-4738-3p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-6873-3p ; hsa-mir-202-5p ; hsa-mir-6845-3p ; hsa-mir-5582-3p ; hsa-mir-2115-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-8067 ; hsa-mir-374b-5p ; hsa-mir-374a-5p ; hsa-mir-3922-5p ; hsa-mir-15a-3p ; hsa-mir-4753-5p ; hsa-mir-4446-5p ; hsa-mir-379-5p ; hsa-mir-3529-5p ; hsa-mir-4650-3p ; hsa-mir-323a-3p ; hsa-mir-590-3p ; hsa-mir-212-3p ; hsa-mir-132-3p
Nearest miRNA
hsa-mir-107/Upstream/782454; hsa-mir-202/Downstream/1870855;
Nearest TSS
ENST00000439456/Upstream/18247; ENST00000433085/Downstream/38024;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/18016, chr10-CpG: 183/Downstream/135869
Upstream sequence
GAAGGATAATTATAACTAGATGCCAGGACAAGGGAAAGCTAGGAGACAGCTGATTTCAATcatcggttcgcagggtgtggtctaaggactcctgagactc
Downstream sequence
tttcagggtgtctgttgaaattgaaactattttcatagttttgcctttttaacttgcaatcccacaaatacatggtagagtttttcagagattactagat
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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