Basic Information
VIS ID
TVIS30005715
Fusion event
HIV-ADAM8 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q26.3
Reference genome
GRCh37/hg19
Start
135081298/133267794 (Hg38)
End
135081298/133267794 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Target gene
ADAM8
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-107/Upstream/20174; hsa-mir-3944/Downstream/103762;
Nearest TSS
ENST00000439456/Upstream/3929; ENST00000482153/Downstream/3631;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/5519, chr10-CpG: 15/Downstream/2441
Upstream sequence
AAGTTCAAGCTCAGATTCTATCATGGCTCAAAGGGGTCTGGGAAGTGCCCACTCCCAAAGCCTCAGTGTTCCCAGCAGGGCGACCACAGCAGCTGCTCTG
Downstream sequence
GGCCTCGGGGCCACCGCTGGCCTGTGCGTGAATTTAATGAAAGGGCTCTGCTGGCCTCGGGCTGCACTTGGGGTCGCAGGATGGGGCCTGGGCACTGCTT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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