Basic Information
VIS ID
TVIS30005731
Fusion event
HIV-AP2A2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p15.5
Reference genome
GRCh37/hg19
Start
955090/955090 (Hg38)
End
955090/955090 (Hg38)
Orient
+
Location type
Intronic
Target gene
AP2A2
miRNAs that regulate target gene
hsa-mir-34a-5p ; hsa-mir-877-3p ; hsa-mir-744-5p ; hsa-mir-92b-3p ; hsa-mir-331-3p ; hsa-mir-93-5p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-210/Upstream/386892; hsa-let-7a-2/Downstream/301515;
Nearest TSS
ENST00000527297/Upstream/8629; ENST00000527917/Downstream/30294;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/10948, chr11-CpG: 56/Downstream/20121
Upstream sequence
CCAGGTTTTTAGTATTTCTGCTTTAGATCTGAGCTCTGTTGATTCTGGACAACATAAGTTCCCCCTCAGAGTGGTTTCTTTCCCTGGTGTTTGGGTGGGT
Downstream sequence
AAAGTAGAGGGCACAAACCAGGGAGAGAGCGCAAGGTCCCCTGTTGCAGACTTAATAGCACAGATCTGTGTACACCTTTGTGAGAAGCACACATGTACAC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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