Basic Information
VIS ID
TVIS30005737
Fusion event
HIV-RRM1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p15.4
Reference genome
GRCh37/hg19
Start
4150743/4129513 (Hg38)
End
4150743/4129513 (Hg38)
Orient
+
Location type
Intronic
Target gene
RRM1
miRNAs that regulate target gene
hsa-mir-192-5p ; hsa-mir-1-3p ; hsa-mir-877-3p ; hsa-let-7i-5p ; hsa-mir-92a-3p ; hsa-mir-1273e ; hsa-mir-7855-5p ; hsa-mir-6807-5p ; hsa-mir-4710 ; hsa-mir-4792 ; hsa-mir-379-5p ; hsa-mir-3529-5p ; hsa-mir-98-5p ; hsa-mir-4500 ; hsa-mir-4458 ; hsa-let-7g-5p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-6840-3p ; hsa-mir-665 ; hsa-mir-4459 ; hsa-mir-6831-5p ; hsa-mir-3927-3p ; hsa-mir-6863
Nearest miRNA
hsa-mir-210/Upstream/273372; hsa-let-7a-2/Downstream/3105253;
Nearest TSS
ENST00000527297/Upstream/7404; ENST00000525365/Downstream/8744;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/34254, chr11-CpG: 71/Downstream/57705
Upstream sequence
ACACACCTAGATTAGGTAATTTTCTTTCTCATTAAGGCTTTTTTCCAACTATGATTTTTTTTTTTAAATGTTTTTCATTCTTATTTATTTCCCAATTTAG
Downstream sequence
TTACATCGGGCATATAAATGGCTTTTGTTTGAATTGATTGTCATAGGAATAATGGATTTTGGAAGAGTTTTTGGAGGGTAATGTGTTTAGACTATATGAA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate