Basic Information
VIS ID
TVIS30005740
Fusion event
HIV-DENND5A integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p15.4
Reference genome
GRCh37/hg19
Start
9221789/9200242 (Hg38)
End
9221789/9200242 (Hg38)
Orient
+
Location type
Intronic
Target gene
DENND5A
miRNAs that regulate target gene
hsa-mir-30d-5p ; hsa-mir-92a-3p ; hsa-mir-25-3p
Nearest miRNA
hsa-mir-210/Upstream/109863; hsa-let-7a-2/Downstream/1308028;
Nearest TSS
ENST00000527297/Upstream/21293; ENST00000630083/Downstream/6476;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/108427, chr11-CpG: 113/Downstream/64484
Upstream sequence
ATTATGTTCATCATATTTGTTTCAATCATCCTTTCCTTGCCTCTAAACACCCCCAATGCCTAAAAGCCTACTGTATCTTCTAACACTCTATATAGTTTGG
Downstream sequence
TTTCCTCCTCTCTGTTCTGTTCTAAACCAGAGAAGTTCCTCCCTATTCAACTAATTCTCCATTTCAAAGTATTTTTATGAAGCTCCAGCCAAGAAATAGC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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