Basic Information
VIS ID
TVIS30005751
Fusion event
HIV-RRAS2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p15.2
Reference genome
GRCh37/hg19
Start
14373917/14352371 (Hg38)
End
14373917/14352371 (Hg38)
Orient
-
Location type
Intronic
Target gene
RRAS2
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-7-5p ; hsa-mir-93-5p ; hsa-mir-26b-5p ; hsa-mir-19b-3p ; hsa-mir-624-3p ; hsa-mir-651-3p ; hsa-mir-23b-3p ; hsa-mir-580-3p ; hsa-mir-4697-3p ; hsa-mir-935 ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-548n ; hsa-mir-223-3p ; hsa-mir-3609 ; hsa-mir-548ah-5p ; hsa-mir-106a-3p ; hsa-mir-3662 ; hsa-mir-2681-5p ; hsa-mir-7848-3p ; hsa-mir-1252-5p ; hsa-mir-944 ; hsa-mir-599 ; hsa-mir-3161 ; hsa-mir-19a-3p ; hsa-mir-4504 ; hsa-mir-549a ; hsa-mir-5590-3p ; hsa-mir-142-5p ; hsa-mir-1255b-2-3p ; hsa-mir-4796-3p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p
Nearest miRNA
hsa-mir-210/Upstream/2188604; hsa-let-7a-2/Downstream/1617162;
Nearest TSS
ENST00000527297/Upstream/10277; ENST00000532740/Downstream/2129;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/92753, chr11-CpG: 110/Downstream/5891
Nearest cancer related gene
RRAS2(OG, No orient, 0)
Upstream sequence
AAGTTAAAGCTGTTCAGTGCTATGCAACAAATAATCACATGGCCTTTATAAAACACtaaaaataaaatataatttataaGACATCAAGGAGCTCAGTCCA
Downstream sequence
ATTATTCTCAAGTACAATTTAAGACAATTTATATTTCTTTGCATCTTTGAAACACATTTTTCTTTGCAAAAGAAATAAATCTAAGGCCTACCAACTACAA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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