Basic Information
VIS ID
TVIS30005753
Fusion event
HIV-HPS5 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p15.1
Reference genome
GRCh37/hg19
Start
18304935/18283388 (Hg38)
End
18304935/18283388 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA11C ; FRA11I
Target gene
HPS5
miRNAs that regulate target gene
hsa-mir-21-5p
Nearest miRNA
hsa-mir-210/Upstream/2313767; hsa-let-7a-2/Downstream/104399;
Nearest TSS
ENST00000527297/Upstream/17124; ENST00000534213/Downstream/3526;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/74029, chr11-CpG: 73/Downstream/38690
Upstream sequence
accgcgcctggccAGAATCATCTTTAATTAATGGGaaattaaaaaaaaaaaaaaaaaaGAGCCTAagcacaaattttggaggaagtccttggtctgaacc
Downstream sequence
ccagctccagcatttacaattagtagctgtgtgactttgggccaattaactgtcccttctgtacctcagttatctggaaagtggaaataatagtaactat
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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