Basic Information
VIS ID
TVIS30005789
Fusion event
HIV-MADD integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
47332534/47310983 (Hg38)
End
47332534/47310983 (Hg38)
Orient
+
Location type
Intronic
Target gene
MADD
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-181a-5p ; hsa-mir-136-5p
Nearest miRNA
hsa-mir-129-2/Upstream/131246; hsa-let-7a-2/Downstream/89987;
Nearest TSS
ENST00000527297/Upstream/18456; ENST00000494403/Downstream/4323;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/40364, chr11-CpG: 19/Downstream/27419
Nearest cancer related gene
MADD(TSG, No orient, 0)
Upstream sequence
gcaacaagagcgaaaatccatctcaaaaaaaaaaaaaaaagaaaTGATGCTCAGAATTTGTTTTTCAGCACAGCCCTATATCTTACAGAATTTTCTATAG
Downstream sequence
TTATAAAAAGAGCCACTCATTAACAAAGTAATAGTAGATTTTAACTTGATTTGGTTGTACTTGGTTTTATAGCTGTGGAAGAAGTATGTTACCAAGTAGA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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