Basic Information
VIS ID
TVIS30005804
Fusion event
HIV-OSBP integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
59358723/59591250 (Hg38)
End
59358723/59591250 (Hg38)
Orient
+
Location type
Intronic
Target gene
OSBP
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-124-3p ; hsa-mir-505-3p ; hsa-mir-365a-3p ; hsa-mir-6878-5p ; hsa-mir-2467-3p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4419a ; hsa-mir-4510 ; hsa-mir-6760-5p ; hsa-mir-6873-5p ; hsa-mir-5197-3p ; hsa-mir-6507-5p ; hsa-mir-3157-5p ; hsa-mir-4671-3p ; hsa-mir-142-3p ; hsa-mir-6073 ; hsa-mir-6077 ; hsa-mir-6770-5p ; hsa-mir-3179 ; hsa-mir-1252-5p ; hsa-mir-4691-3p ; hsa-mir-203a-3p ; hsa-mir-7852-3p ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-3154 ; hsa-mir-5680 ; hsa-mir-4422 ; hsa-mir-6835-3p
Nearest miRNA
hsa-mir-129-2/Upstream/1949964; hsa-let-7a-2/Downstream/3827;
Nearest TSS
ENST00000527297/Upstream/25176; ENST00000531108/Downstream/9342;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/30216, chr11-CpG: 68/Downstream/24189
Upstream sequence
tttaatttatttttaaaatGAAGTCTCCCTAGGATAAATGTTTTAACTTTAAAAAATTAGATCTTTAACAAATTACTAAAAATTAGAAAAAAAATTAGAT
Downstream sequence
CCACCATCTATACCATGTTCATATATTCATTCCTCAAAGAAACCTAGATTAGTCAAATTATAGAGAAAATGTACAATATTTTATTAGTTAAGTTTATTGT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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