Basic Information
VIS ID
TVIS30005922
Fusion event
HIV-UVRAG integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q13.5
Reference genome
GRCh37/hg19
Start
75839902/76128858 (Hg38)
End
75839902/76128858 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA11H
Target gene
UVRAG
miRNAs that regulate target gene
hsa-mir-203a-3p ; hsa-mir-92a-3p ; hsa-mir-130b-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-32-5p ; hsa-mir-615-3p ; hsa-mir-92b-3p ; hsa-mir-33a-5p ; hsa-mir-301a-3p ; hsa-mir-205-5p ; hsa-mir-183-5p ; hsa-mir-203a-5p
Nearest miRNA
hsa-mir-10392/Upstream/793672; hsa-let-7a-2/Downstream/3273164;
Nearest TSS
ENST00000527297/Upstream/12958; ENST00000527314/Downstream/8873;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/312977, chr11-CpG: 79/Downstream/35535
Nearest cancer related gene
UVRAG(TSG, No orient, 0)
Upstream sequence
aggcatgagccaccccgcccagcTGTGACCTTTGGGTTTAAGCTCGATTTAGATATAATTCCCTGtgttttgttttgttttattttgttttAGCCTCTGG
Downstream sequence
ATCCATCTGAGGAAATGCCTTGTGTTTTAATTTTAAAGAGTTTAAATATCATTTTATATGATGTTTATTCTATAATTCTTCTCTTAATGGATAGCAATCT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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