Basic Information
VIS ID
TVIS30005968
Fusion event
HIV-POU2AF1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
111248924/111378199 (Hg38)
End
111248924/111378199 (Hg38)
Orient
-
Location type
Intronic
Target gene
POU2AF1
miRNAs that regulate target gene
hsa-mir-210-3p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p
Nearest miRNA
hsa-mir-10392/Upstream/30375; hsa-let-7a-2/Downstream/134739;
Nearest TSS
ENST00000527297/Upstream/13901; ENST00000375618/Downstream/1076;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/78496, chr11-CpG: 79/Downstream/134244
Upstream sequence
ATGACAGTGTCACATTTTAATCAATGAAGTTATATTTTCCGAACTTTAGTGGATCCAATCAAGTATCTTTCCATAAAATAAAAACATTCCCTAATATATC
Downstream sequence
TTCTTCTGTAAATCTAGATTCTCTTATATTAAGCTTGCTTGAGGCACAGCATACTAAAATTAATTAAAACGAATTTTAAGGAACCAAGAATCTTTAAGAG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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