Basic Information
VIS ID
TVIS30005971
Fusion event
HIV-DLAT integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
111912862/112042138 (Hg38)
End
111912862/112042138 (Hg38)
Orient
-
Location type
Intronic
Target gene
DLAT
miRNAs that regulate target gene
hsa-let-7b-5p ; hsa-mir-615-3p ; hsa-mir-10b-5p ; hsa-mir-8085 ; hsa-mir-5192 ; hsa-mir-6731-5p
Nearest miRNA
hsa-mir-10392/Upstream/528623; hsa-let-7a-2/Downstream/1407885;
Nearest TSS
ENST00000527297/Upstream/16542; ENST00000527231/Downstream/17857;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/16415, chr11-CpG: 28/Downstream/32196
Upstream sequence
gaaatttaagcaaagaagtgaaataaaatgattatgttttgaaaagatcattttggttgctccatggaaatggaTGAAACGTTTATATAGTTTATGTTTG
Downstream sequence
ACAAGATCCCTACTTTTTGTTACCCATAGTCCAGTGTTGTTCCCTTTATACCATATTGCTTTATGATGGCCTGTTGTGCCGCCCAAGAGAGATAGGGAAA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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