Basic Information
VIS ID
TVIS30005993
Fusion event
HIV-MPZL3 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
118120421/118249706 (Hg38)
End
118120421/118249706 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA11B
Target gene
MPZL3
miRNAs that regulate target gene
hsa-mir-4436b-5p ; hsa-mir-664b-3p ; hsa-mir-579-3p ; hsa-mir-5696 ; hsa-mir-671-5p ; hsa-mir-4729 ; hsa-mir-4786-3p ; hsa-mir-449b-3p ; hsa-mir-1228-3p ; hsa-mir-1273g-3p ; hsa-mir-1827 ; hsa-mir-1910-3p ; hsa-mir-2467-3p ; hsa-mir-3612 ; hsa-mir-377-5p ; hsa-mir-4257 ; hsa-mir-4459 ; hsa-mir-455-3p ; hsa-mir-4695-5p ; hsa-mir-4793-3p ; hsa-mir-508-5p ; hsa-mir-6086 ; hsa-mir-6499-3p ; hsa-mir-650 ; hsa-mir-6511a-5p ; hsa-mir-6516-5p ; hsa-mir-665 ; hsa-mir-6807-5p ; hsa-mir-766-3p ; hsa-mir-7703
Nearest miRNA
hsa-mir-10392/Upstream/4799618; hsa-let-7a-2/Downstream/394294;
Nearest TSS
ENST00000527297/Upstream/24612; ENST00000529713/Downstream/2614;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/96227, chr11-CpG: 22/Downstream/109743
Upstream sequence
ACATGAAAGAATTAAATGTGTCAATAAAGCCCCCAATCTTGTATGCCCCATTTTCTAAAATACAAATCTACTGATATTTTATTCATATTGCACACCTAAG
Downstream sequence
TAAAAGAGAGAAAAGTTTAAGAAACCTAGGTCCCCTAGTCTACCATTTCTAAATACTTAGATAACTGATATAGCAGGACCAGACTTATAACTTAAGGAGA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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