Basic Information
VIS ID
TVIS30006011
Fusion event
HIV-CCDC15 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q24.2
Reference genome
GRCh37/hg19
Start
124908624/125038728 (Hg38)
End
124908624/125038728 (Hg38)
Orient
+
Location type
Intronic
Target gene
CCDC15
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-26b-5p ; hsa-mir-1324 ; hsa-mir-218-1-3p ; hsa-mir-4756-3p ; hsa-mir-659-3p ; hsa-mir-7977
Nearest miRNA
hsa-let-7a-2/Upstream/1657216; hsa-mir-3167/Downstream/1949730;
Nearest TSS
ENST00000527297/Upstream/655; ENST00000532000/Downstream/24339;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/84295, chr11-CpG: 83/Downstream/24106
Upstream sequence
ATTTTGGCTCTAGAAGAGACTTGGTAGAACTCATTGTTCTCATTTTCCTTAGAAGAGAATTGACTGTGTCTTTTCATACTTTTCCTCATTTAGGAGTTCA
Downstream sequence
TAACTTCACCAAATTTTTTGATTGCCTAATACTTCTTGGGTGTAGCCCTGCGTTTTTCCCAGTACAAAGAGGAAATGTCAAGGCCCAGAGATACGGAATA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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