Basic Information
VIS ID
TVIS30006021
Fusion event
HIV-APLP2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
129943902/130074007 (Hg38)
End
129943902/130074007 (Hg38)
Orient
-
Location type
Intronic
Target gene
APLP2
miRNAs that regulate target gene
hsa-mir-7-5p ; hsa-mir-346 ; hsa-mir-106b-5p ; hsa-mir-93-5p ; hsa-mir-1260b ; hsa-mir-3671 ; hsa-mir-548v ; hsa-mir-3185 ; hsa-mir-513b-3p ; hsa-mir-30e-5p ; hsa-mir-30d-5p ; hsa-mir-30c-5p ; hsa-mir-30b-5p ; hsa-mir-30a-5p ; hsa-mir-1324 ; hsa-mir-1178-5p ; hsa-mir-1270 ; hsa-mir-148a-3p ; hsa-mir-148b-3p ; hsa-mir-152-3p ; hsa-mir-198 ; hsa-mir-33b-3p ; hsa-mir-3973 ; hsa-mir-4434 ; hsa-mir-4516 ; hsa-mir-4531 ; hsa-mir-455-5p ; hsa-mir-4697-3p ; hsa-mir-515-3p ; hsa-mir-519e-3p ; hsa-mir-520a-5p ; hsa-mir-525-5p ; hsa-mir-5703 ; hsa-mir-6089 ; hsa-mir-620 ; hsa-mir-6507-3p ; hsa-mir-6866-5p
Nearest miRNA
hsa-let-7a-2/Upstream/1551558; hsa-mir-4697/Downstream/592728;
Nearest TSS
ENST00000527297/Upstream/3439; ENST00000461918/Downstream/34598;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/2987, chr11-CpG: 23/Downstream/49622
Upstream sequence
tactcagattcaccaattgttaacatttcttctagtcacatttgctttactactgcattttttgccaaattatttgagagtaagttgcatacgtcgtccc
Downstream sequence
ccatcccctttacccctgagaacttcagtatatattttctaagagccaaagacattgtcttacataggcttagtacagccatcaacctaatgaaatttaa
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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