Basic Information
VIS ID
TVIS30006054
Fusion event
HIV-ING4 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p13.31
Reference genome
GRCh37/hg19
Start
6765066/6655900 (Hg38)
End
6765066/6655900 (Hg38)
Orient
+
Location type
Intronic
Target gene
ING4
miRNAs that regulate target gene
hsa-mir-650 ; hsa-mir-214-3p ; hsa-mir-335-5p ; hsa-mir-1296-3p ; hsa-mir-1343-5p ; hsa-mir-181d-3p ; hsa-mir-2277-3p ; hsa-mir-3065-3p ; hsa-mir-3150a-3p ; hsa-mir-3150b-3p ; hsa-mir-3154 ; hsa-mir-3175 ; hsa-mir-383-3p ; hsa-mir-4434 ; hsa-mir-4481 ; hsa-mir-4516 ; hsa-mir-4745-5p ; hsa-mir-4784 ; hsa-mir-491-5p ; hsa-mir-5187-5p ; hsa-mir-5703 ; hsa-mir-6731-5p ; hsa-mir-6744-5p ; hsa-mir-6757-5p ; hsa-mir-6763-5p ; hsa-mir-6770-5p ; hsa-mir-6825-5p ; hsa-mir-7106-5p ; hsa-mir-7515 ; hsa-mir-765 ; hsa-mir-8085 ; hsa-mir-939-5p
Nearest miRNA
hsa-mir-3649/Upstream/4995520; hsa-let-7i/Downstream/307799;
Nearest TSS
ENST00000382841/Upstream/2503; ENST00000602759/Downstream/857;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/8387, chr12-CpG: 27/Downstream/7192
Nearest cancer related gene
ING4(TSG, No orient, 0)
Upstream sequence
CCTTCAGTGGGTATGGGAATAGCTCCAACAGACATCTTTGAAGAAACCAAGTGAATGCCCCAATGCAGCCAAATTTGCTCAATGTTCCAGGCTGGAGATG
Downstream sequence
GTATCTAATGCTTCTGTAAGTGTGAACGGTATAGAGATCCCATTGTCAATTACTGCttttttttctttcctctttcttttttctttctctttttAAGGAC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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