Basic Information
VIS ID
TVIS30006088
Fusion event
HIV-EPS8 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
15891681/15738747 (Hg38)
End
15891681/15738747 (Hg38)
Orient
-
Location type
Intronic
Target gene
EPS8
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-552-5p ; hsa-mir-589-3p ; hsa-mir-4262 ; hsa-mir-892c-5p ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181b-5p ; hsa-mir-181a-5p ; hsa-mir-606 ; hsa-mir-543 ; hsa-mir-1273f ; hsa-mir-129-5p ; hsa-mir-3529-5p ; hsa-mir-379-5p ; hsa-mir-4451 ; hsa-mir-4534 ; hsa-mir-4650-3p ; hsa-mir-6832-5p ; hsa-mir-8082
Nearest miRNA
hsa-mir-1244-3/Upstream/2822829; hsa-let-7i/Downstream/1934552;
Nearest TSS
ENST00000382841/Upstream/10482; ENST00000544015/Downstream/41321;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/415780, chr12-CpG: 104/Downstream/50037
Nearest cancer related gene
EPS8(OG, No orient, 0)
Upstream sequence
cttaaagcacttgtgttgtatttaatatcagtcatttgtttgcatatttgtctcatagttggaatataaactacaaaaggacacaggccaacttggtttt
Downstream sequence
ttttttgtaataccagcagctacaaagtcctggcaatagcaggtgcttaataaatgtttgttgaatCCACTTACAAGCATACACCTTCACTCCAAGGACC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate