Basic Information
VIS ID
TVIS30006140
Fusion event
HIV-KANSL2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q13.11
Reference genome
GRCh37/hg19
Start
49055668/48661885 (Hg38)
End
49055668/48661885 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA12A
Target gene
KANSL2
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-34a-5p ; hsa-mir-92a-3p
Nearest miRNA
hsa-mir-1244-3/Upstream/7355; hsa-let-7i/Downstream/110090;
Nearest TSS
ENST00000382841/Upstream/3211; ENST00000548054/Downstream/707;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/133539, chr12-CpG: 66/Downstream/19821
Upstream sequence
tggaagaaggatgtatagcagcattcctggcctctatccactagctgtcagtagcacctccatctgagttgtaacaaccaaaaatttctccacacattgc
Downstream sequence
caactggaaaacaaaatggcccccagttgaaaaccactACTCTAAAGAAACAGAAGATAGTACAAGGCAAACAAATATTTATTGAATGATCAAATGAATA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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