Basic Information
VIS ID
TVIS30006185
Fusion event
HIV-PTGES3 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
57057616/56663832 (Hg38)
End
57057616/56663832 (Hg38)
Orient
-
Location type
UTR3
Target gene
PTGES3
miRNAs that regulate target gene
hsa-mir-744-5p ; hsa-mir-106b-5p ; hsa-mir-20a-5p ; hsa-mir-4709-5p ; hsa-mir-3668 ; hsa-mir-186-5p ; hsa-mir-519d-3p ; hsa-mir-93-5p ; hsa-mir-20b-5p ; hsa-mir-17-5p
Nearest miRNA
hsa-mir-1244-3/Upstream/2326518; hsa-let-7i/Downstream/530672;
Nearest TSS
ENST00000382841/Upstream/17764; ENST00000556481/Downstream/24165;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/17793, chr12-CpG: 112/Downstream/23674
Upstream sequence
ACATTTTTCACTCATTTGCCATACTGACAGTGCAAATACAAATCTGGACTAAATGTACAGACTCTCAAGCAACAATGTACAGCTTTCTTCGTCCTCCATG
Downstream sequence
CTAAGAGATGTAAAAGCTTAAGGGTCAAACAATACCAATTGTATAGGCTTCAAAAACCATCTAAGTTAGGGCATTCTCTAGTTTTAGCTAAGATACACCT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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