Basic Information
VIS ID
TVIS30006197
Fusion event
HIV-TMBIM4 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
66546613/66152833 (Hg38)
End
66546613/66152833 (Hg38)
Orient
-
Location type
Intronic
Target gene
TMBIM4
miRNAs that regulate target gene
hsa-mir-138-1-3p ; hsa-mir-330-3p ; hsa-mir-551b-5p ; hsa-mir-6892-5p ; hsa-mir-4746-3p ; hsa-mir-4518 ; hsa-mir-6777-3p ; hsa-mir-1266-5p ; hsa-mir-6823-5p ; hsa-mir-1246 ; hsa-mir-3141 ; hsa-mir-510-5p ; hsa-mir-522-3p ; hsa-mir-224-3p ; hsa-mir-4694-3p ; hsa-mir-6858-5p ; hsa-mir-4689 ; hsa-mir-4784 ; hsa-mir-4749-3p ; hsa-mir-3150b-3p ; hsa-mir-1225-3p ; hsa-mir-6770-5p ; hsa-mir-1253 ; hsa-mir-6761-5p ; hsa-mir-4329 ; hsa-mir-4251 ; hsa-mir-1470 ; hsa-mir-6769a-3p ; hsa-mir-6887-3p ; hsa-mir-4314 ; hsa-mir-5196-5p ; hsa-mir-6506-5p ; hsa-mir-4747-5p ; hsa-mir-619-5p ; hsa-mir-4646-5p ; hsa-mir-3192-5p ; hsa-mir-204-3p ; hsa-mir-4691-3p ; hsa-mir-1298-3p ; hsa-mir-1908-3p ; hsa-mir-6850-3p
Nearest miRNA
hsa-let-7i/Upstream/129107; hsa-mir-1178/Downstream/98249;
Nearest TSS
ENST00000382841/Upstream/13896; ENST00000545837/Downstream/16678;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/21821, chr12-CpG: 63/Downstream/16589
Upstream sequence
TTTAAATTAAAGAATTTTACCTCACATAGCAAACTAATAGTTCAAGACTCCCCTTTGGTGGGGAGAAGGGAAGGGAGGACAGAAATTCTCTACTTCTATG
Downstream sequence
AAAATATTCATTAGTTCTCCTTTCCTTTAATATAACAAAACTGTATCATGGAAATAATTATGATTCATCCCTGATTAAAGATCAGGGATGAATCATGTGG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate