Basic Information
VIS ID
TVIS30006205
Fusion event
HIV-CNOT2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q15
Reference genome
GRCh37/hg19
Start
70644359/70250579 (Hg38)
End
70644359/70250579 (Hg38)
Orient
-
Location type
Intronic
Target gene
CNOT2
miRNAs that regulate target gene
hsa-mir-301b-3p ; hsa-mir-361-5p ; hsa-let-7b-5p ; hsa-mir-7703 ; hsa-mir-4325 ; hsa-mir-889-3p ; hsa-mir-548au-3p ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-367-3p ; hsa-mir-363-3p ; hsa-mir-32-5p ; hsa-mir-25-3p ; hsa-mir-5003-3p ; hsa-mir-935 ; hsa-mir-9500 ; hsa-mir-1264
Nearest miRNA
hsa-let-7i/Upstream/665756; hsa-mir-1178/Downstream/9168678;
Nearest TSS
ENST00000382841/Upstream/6828; ENST00000547867/Downstream/27553;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/6610, chr12-CpG: 144/Downstream/115078
Upstream sequence
acggtgatccagacaagtctccaccttcattaatgtaacattctggaggaggagacagacagtaaacaaataaataaacataatttcaggtaatggtaac
Downstream sequence
ttaggaaaaaataaagggggataaaggtacagcaattgattagaaatggaaaaaagattaagtagggtgatgagagaagacttctgtggaggtatcagtt
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate