Basic Information
VIS ID
TVIS30006225
Fusion event
HIV-LTA4H integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
96407903/96014125 (Hg38)
End
96407903/96014125 (Hg38)
Orient
+
Location type
Intronic
Target gene
LTA4H
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-26b-5p ; hsa-mir-125b-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p
Nearest miRNA
hsa-let-7i/Upstream/704141; hsa-mir-1178/Downstream/1477784;
Nearest TSS
ENST00000382841/Upstream/873; ENST00000547346/Downstream/199;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/18228, chr12-CpG: 41/Downstream/21111
Upstream sequence
AGTTGGGCCTTGAAGAATATATGTAATTCAGTGGAAGGGAGAAGAGAAATTCTAATTATAGGTAAGGGGATAACACATGAAGACACAGAAAAGGAATGCA
Downstream sequence
TAACCCAAGTTCTAAAAGCAATAACCTTCACATGACTAGAAAGGAGAAAAATAAGACTGGACAGGCAGAATGGATCCAGGTGACAGACAGCCTTCCAAGT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate