Basic Information
VIS ID
TVIS30006289
Fusion event
HIV-C12orf65 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q24.31
Reference genome
GRCh37/hg19
Start
123736192/123251645 (Hg38)
End
123736192/123251645 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA12E
Target gene
C12orf65
miRNAs that regulate target gene
hsa-mir-130b-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-331-3p ; hsa-mir-222-3p ; hsa-mir-5089-5p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-150-5p ; hsa-mir-186-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-6504-3p ; hsa-mir-512-3p ; hsa-mir-576-3p ; hsa-mir-5683 ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p
Nearest miRNA
hsa-let-7i/Upstream/240917; hsa-mir-3612/Downstream/113119;
Nearest TSS
ENST00000382841/Upstream/3367; ENST00000429587/Downstream/1745;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/17804, chr12-CpG: 27/Downstream/17857
Upstream sequence
gctgagtctgacttagctccaggtaaagttggaaatttctcctgcaaacagaccttcagcctctccagtgggggggtgtgtgttcgggagaggaggatct
Downstream sequence
ccctttcccacttccacagttggggcactcacagtatttgggggtctcccgggccctgcaggagcaatccgcttccttcagagggtctgtgggtcctctc
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate