Basic Information
VIS ID
TVIS30006358
Fusion event
HIV-INTS6 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
51994241/51420105 (Hg38)
End
51994241/51420105 (Hg38)
Orient
+
Location type
Intronic
Target gene
INTS6
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-1-3p ; hsa-mir-30a-5p ; hsa-mir-192-3p ; hsa-mir-4662a-5p ; hsa-mir-616-3p ; hsa-mir-4317 ; hsa-mir-95-5p
Nearest miRNA
hsa-mir-15a/Upstream/71466; hsa-mir-1267/Downstream/132484;
Nearest TSS
ENST00000623511/Upstream/34841; ENST00000598905/Downstream/1269;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/168197, chr13-CpG: 186/Downstream/31450
Nearest cancer related gene
INTS6(TSG, No orient, 0)
Upstream sequence
tgcttttgccctccaacagtggaatagttccagtacacactatacaggctgaaaaacctaaaatgttcactatctggcccttcaaagaaaatgtttgctg
Downstream sequence
acccctagtataaatcatgatccatgttattcaagaagcaaagatcagaatttcctttgtataaattttttcctctcatctttttaaagttctattttaa
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate