Basic Information
VIS ID
TVIS30006396
Fusion event
HIV-MBNL2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q32.1
Reference genome
GRCh37/hg19
Start
97946565/97294311 (Hg38)
End
97946565/97294311 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA13D
Target gene
MBNL2
miRNAs that regulate target gene
hsa-mir-372-3p ; hsa-mir-302d-3p ; hsa-mir-218-5p ; hsa-mir-335-5p ; hsa-mir-101-3p ; hsa-mir-98-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-5011-5p ; hsa-mir-369-3p ; hsa-mir-30a-5p ; hsa-mir-30b-5p ; hsa-mir-30e-5p ; hsa-mir-5583-3p ; hsa-mir-297 ; hsa-mir-3924 ; hsa-mir-190a-3p ; hsa-mir-223-5p ; hsa-mir-567 ; hsa-mir-511-3p ; hsa-mir-410-3p ; hsa-mir-374a-5p ; hsa-mir-374b-5p ; hsa-mir-10b-5p
Nearest miRNA
hsa-mir-1297/Upstream/867019; hsa-mir-1267/Downstream/914213;
Nearest TSS
ENST00000623511/Upstream/71956; ENST00000449284/Downstream/62485;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/299828, chr13-CpG: 34/Downstream/52397
Upstream sequence
TTTCTTTTTTCTCCTACTGTTTCCAAAACCCCTCACCAATTAATGAATGACTCTGTTCAATATTGTGCCATACTCCCtgcaagacacatggaaatgtaac
Downstream sequence
actcagttcttgttcttagggattttataaactaactaggagacagatagccatgcagaatttacaatTAAATACTAAACCATGTGTACCGGTTATTAGC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate