Basic Information
VIS ID
TVIS30006397
Fusion event
HIV-MBNL2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q32.1
Reference genome
GRCh37/hg19
Start
98014369/97362115 (Hg38)
End
98014369/97362115 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA13D
Target gene
MBNL2
miRNAs that regulate target gene
hsa-mir-372-3p ; hsa-mir-302d-3p ; hsa-mir-218-5p ; hsa-mir-335-5p ; hsa-mir-101-3p ; hsa-mir-98-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-5011-5p ; hsa-mir-369-3p ; hsa-mir-30a-5p ; hsa-mir-30b-5p ; hsa-mir-30e-5p ; hsa-mir-5583-3p ; hsa-mir-297 ; hsa-mir-3924 ; hsa-mir-190a-3p ; hsa-mir-223-5p ; hsa-mir-567 ; hsa-mir-511-3p ; hsa-mir-410-3p ; hsa-mir-374a-5p ; hsa-mir-374b-5p ; hsa-mir-10b-5p
Nearest miRNA
hsa-mir-1297/Upstream/934823; hsa-mir-1267/Downstream/846409;
Nearest TSS
ENST00000623511/Upstream/5319; ENST00000476869/Downstream/72107;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/14992, chr13-CpG: 154/Downstream/70851
Upstream sequence
cccacctcagcctcccaaagtgctgggattacaggcgtgagccactgtgcccagccATTTTTTTATGAGTAcaagttgagtgccccttgatccaaaatgc
Downstream sequence
ttgggaccagaaatatttcagattttggatttttttttcagattttggaatatttggattacattaacagttgagcatcccatatttgaaaatctgaaat
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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