Basic Information
VIS ID
TVIS30006400
Fusion event
HIV-DOCK9 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q32.3
Reference genome
GRCh37/hg19
Start
99533678/98881424 (Hg38)
End
99533678/98881424 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA13D
Target gene
DOCK9
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-32-5p ; hsa-mir-16-5p ; hsa-mir-214-3p ; hsa-mir-218-5p ; hsa-mir-4477a ; hsa-mir-889-3p ; hsa-mir-1295b-3p ; hsa-mir-3142 ; hsa-mir-1245b-5p ; hsa-mir-1277-5p ; hsa-mir-92b-3p ; hsa-mir-92a-3p
Nearest miRNA
hsa-mir-1297/Upstream/672824; hsa-mir-1267/Downstream/474707;
Nearest TSS
ENST00000623511/Upstream/20948; ENST00000562781/Downstream/7261;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/128575, chr13-CpG: 222/Downstream/204653
Upstream sequence
GAAAACCCATTAAAAGAAACATAATTGAAGGAATGGAATTAAGTAAATTAGTGAATGGCTGTCCCTCTTCGTACCTCCCCTATTCAGGTACAAGCATTGG
Downstream sequence
CTATGAGAAATAGAAGAGAAAGCATACGTTACAAGCACATCCTCAAATAACCAGGCTTGTGAAAAAATAAGTCCTTAGAAGGAAAACTGGAGAGCCACAG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate