Basic Information
VIS ID
TVIS30006428
Fusion event
HIV-NEDD8 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q12
Reference genome
GRCh37/hg19
Start
24695518/24226312 (Hg38)
End
24695518/24226312 (Hg38)
Orient
-
Location type
Intronic
Target gene
NEDD8
miRNAs that regulate target gene
hsa-mir-1276 ; hsa-mir-133a-5p ; hsa-mir-4311 ; hsa-mir-583
Nearest miRNA
hsa-mir-208a/Upstream/82747; hsa-mir-1185-1/Downstream/2682330;
Nearest TSS
ENST00000550708/Upstream/7586; ENST00000559801/Downstream/5690;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/12681, chr14-CpG: 28/Downstream/6128
Upstream sequence
tgggcacagtggctcacgcttgtaatcccagcagtttgggaggctgaggcaggtggatcacttgaggtcaggagttcgagaccagcatggccaacatggc
Downstream sequence
aaaaccctgtctctaccaaaaatacaaaaaaattagctaggcatggtggacgcttgaacgaaggtggaggttgcagtgagccgagatcgtgccaccgcac
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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