Basic Information
VIS ID
TVIS30006433
Fusion event
HIV-HECTD1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q12
Reference genome
GRCh37/hg19
Start
31611026/31141820 (Hg38)
End
31611026/31141820 (Hg38)
Orient
+
Location type
Intronic
Target gene
HECTD1
miRNAs that regulate target gene
hsa-mir-210-3p ; hsa-mir-335-5p ; hsa-mir-30a-5p ; hsa-mir-21-5p ; hsa-mir-221-3p ; hsa-mir-142-3p ; hsa-mir-374a-5p ; hsa-mir-6073 ; hsa-mir-20b-3p ; hsa-mir-6514-5p ; hsa-mir-4802-5p ; hsa-mir-4280 ; hsa-mir-1183 ; hsa-mir-203a-3p ; hsa-mir-4668-5p ; hsa-mir-3613-3p ; hsa-mir-5002-5p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-92b-3p
Nearest miRNA
hsa-mir-208a/Upstream/127078; hsa-mir-1185-1/Downstream/5810489;
Nearest TSS
ENST00000550708/Upstream/4982; ENST00000551799/Downstream/26521;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/114970, chr14-CpG: 167/Downstream/64985
Upstream sequence
ATACATGTATAATATGTTACTTTCTTATTAAGAGTTTCTTTTGTGTGCATAAATGTTACACTAGACTTATTTTAGAGGAAGTATACCAACTGTGTGAACA
Downstream sequence
TTACAAACATCAAATTCAAAGAAATTTGAGATTTTACCTTTCATCATCTTCATTTTCACTAAAGGCAGTTTTAAAAACATTTATTCTTTCTACCAGTTGA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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