Basic Information
VIS ID
TVIS30006442
Fusion event
HIV-MIPOL1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
37687525/37218320 (Hg38)
End
37687525/37218320 (Hg38)
Orient
-
Location type
Intronic
Target gene
MIPOL1
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-let-7a-3p ; hsa-mir-1277-5p ; hsa-mir-4666b ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-6867-5p ; hsa-mir-3650 ; hsa-mir-380-3p ; hsa-mir-411-3p ; hsa-mir-379-3p ; hsa-mir-4495 ; hsa-mir-4517 ; hsa-mir-5001-3p ; hsa-mir-4279 ; hsa-mir-4497 ; hsa-mir-5581-5p ; hsa-mir-4297 ; hsa-mir-6778-3p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-150-5p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-6814-5p ; hsa-mir-122-3p ; hsa-mir-96-5p ; hsa-mir-1271-5p ; hsa-mir-183-5p ; hsa-mir-593-5p ; hsa-mir-5571-5p
Nearest miRNA
hsa-mir-208a/Upstream/265929; hsa-mir-1185-1/Downstream/10542675;
Nearest TSS
ENST00000550708/Upstream/20233; ENST00000554114/Downstream/1232;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/20032, chr14-CpG: 123/Downstream/365120
Upstream sequence
cccaggctggagtgcagtggcacaatctcagctcacttcagcctccacctcccagattcaagcaattctcacgtctcagcctcccgagtagctgggatta
Downstream sequence
caagtgtgcaccaaaatgcctggctcatttttgtattttttttttttaatagaggtggggtttcaccatgttggccaggctgatctggaactcctgacct
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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