Basic Information
VIS ID
TVIS30006467
Fusion event
HIV-CHURC1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
65390738/64924020 (Hg38)
End
65390738/64924020 (Hg38)
Orient
+
Location type
Exonic
Fragile sites / regions
FRA14B
Target gene
CHURC1
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-93-5p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-17-5p
Nearest miRNA
hsa-mir-208a/Upstream/138334; hsa-mir-1185-1/Downstream/120668;
Nearest TSS
ENST00000550708/Upstream/10; ENST00000553743/Downstream/16;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/9356, chr14-CpG: 81/Downstream/47674
Upstream sequence
AGTCTGTTAATCATCTTCACTAAAGATTTTGAAATGTAAAGAAATTAAATTCCTGTTTCTGATATTTTAGGGTAATACCTGCCTGGAGAATGGATCTTTC
Downstream sequence
TTACTGAACTTTACAGGCTGTGCAGTGTGCAGTAAGCGGGATTTTATGCTGATCACAAACAAATCCTTGAAAGAAGAAGATGGAGAAGAAATAGTTACCT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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