Basic Information
VIS ID
TVIS30006475
Fusion event
HIV-GPHN integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
67295181/66828463 (Hg38)
End
67295181/66828463 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA14B
Target gene
GPHN
miRNAs that regulate target gene
hsa-let-7b-5p ; hsa-mir-375
Nearest miRNA
hsa-mir-208a/Upstream/1357277; hsa-mir-1185-1/Downstream/613392;
Nearest TSS
ENST00000550708/Upstream/3989; ENST00000556501/Downstream/141353;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/318946, chr14-CpG: 95/Downstream/412573
Upstream sequence
TTAGAAATATAATCCTCGCTGAATTATATACTGATTTGTCTGTTTTGATAGTTGTATCTAAAGAGAAGAAGCTGTTTCTAGACACATTTACCTATATTAT
Downstream sequence
ATACATCAGGATTGCCAATATTTTTAAATGAGGTCAGAAGTTATTGGTAGAAAGCACAAATACTAATTTGATAAAAGTAAAACAATGTAAAACTTCTCCC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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