Basic Information
VIS ID
TVIS30006487
Fusion event
HIV-SIPA1L1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q24.2
Reference genome
GRCh37/hg19
Start
72054506/71587789 (Hg38)
End
72054506/71587789 (Hg38)
Orient
+
Location type
UTR5
Target gene
SIPA1L1
miRNAs that regulate target gene
hsa-mir-92a-3p ; hsa-mir-4531 ; hsa-mir-5581-3p ; hsa-mir-5703 ; hsa-mir-4516 ; hsa-mir-4434 ; hsa-mir-539-5p ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181b-5p ; hsa-mir-181a-5p
Nearest miRNA
hsa-mir-208a/Upstream/4145859; hsa-mir-1185-1/Downstream/929031;
Nearest TSS
ENST00000550708/Upstream/1508; ENST00000555066/Downstream/10445;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/266281, chr14-CpG: 114/Downstream/344158
Upstream sequence
AGAAGTTCCAATTTTTCAGTGCTTTACAAATAAAGCATCATTTAACCTTTTAAATGAAAAAGATTAAGATCTCATGCAACTGTTGTATTTTCTGGAAGCC
Downstream sequence
ATTCTCCAAAAGGGAAGTGCACATTTAAAACACAGATATGATGGTCCTTGCTGCAGGGATTTAAGTCTACTTGCTTTTACATCATGACCAGCTTGAAACG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate