Basic Information
VIS ID
TVIS30006517
Fusion event
HIV-TRIP11 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q32.12
Reference genome
GRCh37/hg19
Start
92480297/92013953 (Hg38)
End
92480297/92013953 (Hg38)
Orient
+
Location type
Intronic
Target gene
TRIP11
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-150-5p ; hsa-mir-6862-3p ; hsa-mir-6784-3p ; hsa-mir-1224-3p ; hsa-mir-186-3p ; hsa-mir-3620-3p ; hsa-mir-6865-3p ; hsa-mir-148a-5p ; hsa-mir-599 ; hsa-mir-3161 ; hsa-mir-4639-3p ; hsa-mir-640 ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-203b-3p ; hsa-mir-7158-3p ; hsa-mir-378a-5p ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-4680-5p ; hsa-mir-4635 ; hsa-mir-3653-5p ; hsa-mir-6852-3p ; hsa-mir-3909 ; hsa-mir-6735-3p ; hsa-mir-214-5p ; hsa-mir-520f-5p ; hsa-mir-4509 ; hsa-mir-4744 ; hsa-mir-5699-3p ; hsa-mir-4421 ; hsa-mir-6507-3p
Nearest miRNA
hsa-mir-1260a/Upstream/14747663; hsa-mir-1185-1/Downstream/1934273;
Nearest TSS
ENST00000550708/Upstream/14574; ENST00000553427/Downstream/1798;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/65973, chr14-CpG: 71/Downstream/25701
Upstream sequence
AAAATGGTGGAAGACCTATGGCTCTAAGCACTCAGGGCTTTGCTTGGATATAGGAGATCGTTTCAAACAGGTAACAACTGACTTTGAAGAAGAAAGGCTG
Downstream sequence
TATTCCCTAACTGGAGGATGTGGGCTGTGATGAGTTACAGAAAGTATAGCAATACCTAATCCTTTTTAATAGGAAATTCCTATTTGCAATCTATTAACTC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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