Basic Information
VIS ID
TVIS30006536
Fusion event
HIV-TRAF3 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q32.32
Reference genome
GRCh37/hg19
Start
103282575/102816238 (Hg38)
End
103282575/102816238 (Hg38)
Orient
+
Location type
Intronic
Target gene
TRAF3
miRNAs that regulate target gene
hsa-mir-32-5p ; hsa-mir-26b-5p ; hsa-mir-3191-3p ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-4707-3p ; hsa-mir-6746-5p ; hsa-mir-574-5p ; hsa-mir-4455 ; hsa-mir-129-5p ; hsa-mir-6867-5p ; hsa-mir-4694-5p ; hsa-mir-4286 ; hsa-mir-662 ; hsa-mir-3178 ; hsa-mir-34a-5p ; hsa-mir-361-3p ; hsa-mir-3679-3p ; hsa-mir-4639-3p ; hsa-mir-548e-5p ; hsa-mir-6777-3p ; hsa-mir-6805-5p ; hsa-mir-6846-5p ; hsa-mir-6848-5p
Nearest miRNA
hsa-mir-1185-1/Upstream/276512; hsa-mir-12121/Downstream/1301167;
Nearest TSS
ENST00000550708/Upstream/38620; ENST00000558880/Downstream/14116;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/37870, chr14-CpG: 27/Downstream/91262
Upstream sequence
gttgcccaggcaggagtgtagtgatgccatctcagttctcttcaacctccgcctcctgggctcaggtgatcctctcacctcagccccccaagtagctggg
Downstream sequence
actacgagcacatgccaccaccctcgcctaatttttgtattttttgtagagatggggttttaccatgttggccaggctggtctcgaactcctgagctcaa
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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