Basic Information
VIS ID
TVIS30006576
Fusion event
HIV-RASGRP1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q14
Reference genome
GRCh37/hg19
Start
38852142/38559941 (Hg38)
End
38852142/38559941 (Hg38)
Orient
+
Location type
Exonic
Target gene
RASGRP1
miRNAs that regulate target gene
hsa-mir-21-5p ; hsa-mir-335-5p ; hsa-mir-125b-5p ; hsa-mir-4652-3p ; hsa-mir-4743-3p ; hsa-mir-3180-5p ; hsa-mir-525-5p ; hsa-mir-520a-5p ; hsa-mir-488-5p ; hsa-mir-599 ; hsa-mir-3161 ; hsa-mir-4679 ; hsa-mir-4677-3p ; hsa-mir-29a-3p ; hsa-mir-4517 ; hsa-mir-4524b-3p ; hsa-mir-4645-3p ; hsa-mir-5583-3p
Nearest miRNA
hsa-mir-1233-1/Upstream/1587040; hsa-mir-10393/Downstream/3131644;
Nearest TSS
ENST00000557528/Upstream/35871; ENST00000557946/Downstream/141;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/105357, chr15-CpG: 137/Downstream/4120
Upstream sequence
CAATGAGATCGTCCAGGCTGGCTCCTTTGGCTAAATGTCCCAGAGACACCATCATTCGGAACTGGGTGATGTGGGCCAAGCTGGGATGGGAGGGGAAGGG
Downstream sequence
GCTGTTGGCTGGCTTTGCCTCTAGTCTTGCTTTAGAGGCAGCTCTGCAGCCATGGGAAGGTTTCCTGGGGAAAGAGAGAAGGCAGTGAGGGGACAAACGG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate