Basic Information
VIS ID
TVIS30006577
Fusion event
HIV-EIF2AK4 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q15.1
Reference genome
GRCh37/hg19
Start
40325991/40033790 (Hg38)
End
40325991/40033790 (Hg38)
Orient
-
Location type
Intronic
Target gene
EIF2AK4
miRNAs that regulate target gene
hsa-mir-3658 ; hsa-mir-7856-5p ; hsa-mir-499a-5p ; hsa-mir-208b-3p ; hsa-mir-208a-3p ; hsa-mir-641 ; hsa-mir-4282 ; hsa-mir-3617-5p
Nearest miRNA
hsa-mir-1233-1/Upstream/3060889; hsa-mir-10393/Downstream/1657795;
Nearest TSS
ENST00000557528/Upstream/3397; ENST00000560341/Downstream/5083;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/56930, chr15-CpG: 48/Downstream/5000
Upstream sequence
GTCAAATGGATATACTTAAGAGCTGCTATCACCGTTGTACAAAAAGTAAACAGAggccgggtgcagtggctcacgcctgtaatcccagcactttgggagg
Downstream sequence
ccgacgtgggtggatcacctgaggtctggggtttgagaccagcctggccaacatggtgaaaccccatctctactaaaaatacaaaaaattagccgggcgt
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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