Basic Information
VIS ID
TVIS30006591
Fusion event
HIV-TP53BP1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q15.3
Reference genome
GRCh37/hg19
Start
43767658/43475460 (Hg38)
End
43767658/43475460 (Hg38)
Orient
-
Location type
Intronic
Target gene
TP53BP1
miRNAs that regulate target gene
hsa-mir-505-3p ; hsa-mir-361-5p ; hsa-mir-182-5p
Nearest miRNA
hsa-mir-1233-1/Upstream/1275794; hsa-mir-10393/Downstream/318199;
Nearest TSS
ENST00000557528/Upstream/19129; ENST00000382031/Downstream/17626;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/103992, chr15-CpG: 22/Downstream/17585
Nearest cancer related gene
TP53BP1(TSG, No orient, 0)
Upstream sequence
GGCTACTATTATAAAATTTTCAAATGGGACAACAGATTTATCTGCcttcaacagttcttcatccccaaagctctaatgcataggttctaccatttggttt
Downstream sequence
caAAAAGAATTCTAGACTAGCAGATAAGTTTAGCCTCTTTCAGCCTTAGCCTAAGACTCTCAGGCACATACTGCCTTGGCATAAGCTATTTTAGGCTTAC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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