Basic Information
VIS ID
TVIS30006607
Fusion event
HIV-ADAM10 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
59040225/58748026 (Hg38)
End
59040225/58748026 (Hg38)
Orient
-
Location type
Intronic
Target gene
ADAM10
miRNAs that regulate target gene
hsa-mir-122-5p ; hsa-mir-155-5p ; hsa-mir-484 ; hsa-mir-32-5p ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-451a ; hsa-mir-103a-3p ; hsa-mir-448 ; hsa-mir-655-3p ; hsa-mir-449a
Nearest miRNA
hsa-mir-10393/Upstream/3374992; hsa-mir-11181/Downstream/423157;
Nearest TSS
ENST00000557528/Upstream/68744; ENST00000559745/Downstream/940;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/681448, chr15-CpG: 125/Downstream/856
Upstream sequence
ACAGTGTCTTAACTCCTGAATTTAATCACAAAAAGTGAAAAAAGATAGGAAAACGATTTGTTGAAAGCCACGTTTAGAACAGAAATAACAAATGTCAGAT
Downstream sequence
GAAAAAGGCTCCTCTAACAGAGAGTCTCCCGCACATAATCCTTTTTAAAACTAAACATCTATTATCAGCTCTTAATCTATAATGTGTGTCTTGCTTGATG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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