Basic Information
VIS ID
TVIS30006622
Fusion event
HIV-TLN2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
62797192/62504993 (Hg38)
End
62797192/62504993 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA15A
Target gene
TLN2
miRNAs that regulate target gene
hsa-mir-194-5p ; hsa-mir-132-3p ; hsa-mir-4314 ; hsa-mir-6508-3p ; hsa-mir-4726-5p ; hsa-mir-4640-5p ; hsa-mir-378g ; hsa-mir-4486 ; hsa-mir-6860 ; hsa-mir-612 ; hsa-mir-5189-5p ; hsa-mir-3187-5p ; hsa-mir-1285-3p ; hsa-mir-4328 ; hsa-mir-25-5p ; hsa-mir-658 ; hsa-mir-6087 ; hsa-mir-6804-5p ; hsa-mir-6856-5p ; hsa-mir-6758-5p
Nearest miRNA
hsa-mir-10393/Upstream/161855; hsa-mir-11181/Downstream/318964;
Nearest TSS
ENST00000557528/Upstream/51401; ENST00000474847/Downstream/56372;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/112796, chr15-CpG: 21/Downstream/192722
Nearby gene
MGC15885(No orient, 132179)
Upstream sequence
CTCTGCCCCACTGCTCACTTTTTTGTTGGGTAATAACATTAAAAAACAGAAACAtgtttttgttgttgttgttgttgttttgagacggagtctcactctg
Downstream sequence
ttccccaggctggagtgtagtggcgcgatctcagctcactgcaacctccgcttcccaggttcaagcgattctcctgcctcagcttcccgagtagctggga
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate