Basic Information
VIS ID
TVIS30006631
Fusion event
HIV-MTFMT integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q22.31
Reference genome
GRCh37/hg19
Start
65316747/65024409 (Hg38)
End
65316747/65024409 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA15A
Target gene
MTFMT
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-935 ; hsa-mir-6773-5p ; hsa-mir-6724-5p ; hsa-mir-1273e ; hsa-mir-296-5p ; hsa-mir-6894-5p ; hsa-mir-4722-5p ; hsa-mir-6774-5p ; hsa-mir-635 ; hsa-mir-6840-3p ; hsa-mir-665 ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-3714 ; hsa-mir-513b-5p ; hsa-mir-4786-5p ; hsa-mir-6849-3p ; hsa-mir-4768-3p ; hsa-mir-1288-5p ; hsa-mir-125b-2-3p ; hsa-mir-4457 ; hsa-mir-4293 ; hsa-mir-624-3p ; hsa-mir-3974
Nearest miRNA
hsa-mir-10393/Upstream/261894; hsa-mir-11181/Downstream/694837;
Nearest TSS
ENST00000557528/Upstream/34099; ENST00000334287/Downstream/2522;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/34372, chr15-CpG: 62/Downstream/4684
Upstream sequence
agcgaaactccgtcgcaaaaTCTACAACAGCCCATGATGTCTGGGAGtttttaaataaaattttaaaatGCATTTATGACTATAAGAGAACCACTCAAAC
Downstream sequence
CCTATTATGCATCTCATGAACAATTCTAATTTTATAGTTTAGTCACATAACTATCCTCACTTCACTTGGTTTACATACAGACTGCCTAAAATAAGCtttt
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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