Basic Information
VIS ID
TVIS30006644
Fusion event
HIV-PML integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
74293134/74000793 (Hg38)
End
74293134/74000793 (Hg38)
Orient
-
Location type
Intronic
Target gene
PML
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-423-3p ; hsa-mir-378a-3p
Nearest miRNA
hsa-mir-10393/Upstream/700814; hsa-mir-11181/Downstream/410564;
Nearest TSS
ENST00000557528/Upstream/2769; ENST00000569161/Downstream/22112;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/2374, chr15-CpG: 60/Downstream/22044
Nearest cancer related gene
PML(TSG, No orient, 0)
Upstream sequence
tttgaatttgtatatttttttattgtggtacttttttaattgattttttttcgcctgaatatttttgatccaagatttgttgaatccacgggtgcgtaac
Downstream sequence
ctgcagatactgagggccaactgtacatataaattgtttagcgtagtgcctggcacatattaaatactcagtgaatgttaaaattctattatAAtttctc
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate