Basic Information
VIS ID
TVIS30006645
Fusion event
HIV-PML integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
74299906/74007565 (Hg38)
End
74299906/74007565 (Hg38)
Orient
+
Location type
Intronic
Target gene
PML
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-423-3p ; hsa-mir-378a-3p
Nearest miRNA
hsa-mir-10393/Upstream/707586; hsa-mir-11181/Downstream/403792;
Nearest TSS
ENST00000557528/Upstream/9541; ENST00000569161/Downstream/15340;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/9146, chr15-CpG: 60/Downstream/15272
Nearest cancer related gene
PML(OG, No orient, 0)
Upstream sequence
TGTTTCACAATTTACCAGTGGTTACTGGACAAACTCAACTTATTTTTTCTGCACAAAACTTCAATGCCATAAATAAGAGCTCACAACTTTCCTCTGGTCA
Downstream sequence
CAAGTCAGTTAGCAGCCACCTCGCTCTTTGACCCTGGGCTGATTTAGAGCTCACACTGGGGAGCAGCCCCAGAGGTGGCTTTAAACCTGGGACTCGGGGT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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