Basic Information
VIS ID
TVIS30006772
Fusion event
HIV-MRTFB integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p13.12
Reference genome
GRCh37/hg19
Start
14341608/14247751 (Hg38)
End
14341608/14247751 (Hg38)
Orient
+
Location type
Intronic
Target gene
MRTFB
miRNAs that regulate target gene
hsa-mir-29c-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-607 ; hsa-mir-3156-3p ; hsa-mir-3671 ; hsa-mir-4433a-5p ; hsa-mir-3907 ; hsa-mir-3145-3p ; hsa-mir-139-5p ; hsa-mir-4735-5p ; hsa-mir-4301 ; hsa-mir-181a-2-3p ; hsa-mir-4762-5p ; hsa-mir-5002-5p ; hsa-mir-5588-3p ; hsa-mir-32-3p ; hsa-mir-6715b-3p ; hsa-mir-1256 ; hsa-mir-8076 ; hsa-mir-3688-3p ; hsa-mir-183-5p ; hsa-mir-190a-5p ; hsa-mir-190b ; hsa-mir-19b-3p ; hsa-mir-19a-3p
Nearest miRNA
hsa-mir-1225/Upstream/1527380; hsa-mir-11401/Downstream/56216;
Nearest TSS
ENST00000527434/Upstream/340; ENST00000571770/Downstream/10372;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/175952, chr16-CpG: 54/Downstream/37716
Nearest cancer related gene
MRTFB(OG, No orient, 0)
Upstream sequence
ATTCAGAAATCTGAATATCTAGCACTGTTTTTATATAGTGAAAAAAACACAGGATGCTTTTCTAGTCCTGTTACCTTTTCCCTTGAATGAACACAGTATC
Downstream sequence
ATCCATGCAGACATTTTTTTACACACCAGTGACGTGATCATTGTGATCATAGTCTGCCGCtgagcactttctggcaaggcacagcatctagtactttaaa
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate